Cell Host Microbe
2021 Jun 9;29(6):1002-1013.e9. doi: 10.1016/j.chom.2021.03.019. Epub 2021 Apr 28.
Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism
Jessica N Witchley 1, Pauline Basso 1, Cedric A Brimacombe 1, Nina V Abon 1, Suzanne M Noble 2 (PDF)
A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans (2019)
CA Brimacombe, JE Burke, JY Parsa, S Catania, TR O’Meara, J Witchley, L Burrack, H Madhani, SM Noble (PDF)
Candida albicans morphogenesis programs control the balance between gut commensalism and invasive infection (2019)
JN Witchley, P Penumetcha, NV Abon, CA Woolford, AP Mitchell, SM Noble
Cell Host & Microbe 25 (3), 432-443. e6 ( PDF )
High-throughput screening identifies genes required for Candida albicans induction of macrophage pyroptosis (2018)
TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ...
mBio 9 (4), e01581-18
Chromatin rewiring mediates programmed evolvability via aneuploidy (2018)
C Brimacombe, J Burke, JY Parsa, J Witchley, L Burrack, H Madhani, SM Noble
bioRxiv, 407841
Candida albicans cell-type switching and functional plasticity in the mammalian host (2017)
SM Noble, BA Gianetti, JN Witchley
Nature Reviews Microbiology 15 (2), 96 ( PDF )
Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom interactions of Pseudomonas aeruginosa (2014)
VV Phelan, WJ Moree, J Aguilar, DS Cornett, A Koumoutsi, SM Noble, ...
Journal of Bacteriology 196 (9), 1683-1693 ( PDF | Supplemental Information )
Candida albicans specializations for iron homeostasis: from commensalism to virulence (2013)
SM Noble
Current Opinion in Microbiology 16 (6), 708-715 ( PDF )
Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism (2013)
K Pande, C Chen, SM Noble
Nature Genetics 45 (9), 1088 ( PDF | Supplemental Information S1 | Supplemental Information S2 )
Post-transcriptional regulation of the Sef1 transcription factor controls the virulence of Candida albicans in its mammalian host (2012)
C Chen, SM Noble
PLoS Pathogens 8 (11), e1002956 ( PDF )
An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis (2011)
C Chen, K Pande, SD French, BB Tuch, SM Noble
Cell Host & Microbe 10 (2), 118-135 ( PDF | Supplemental Information )
Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity (2010)
SM Noble, S French, LA Kohn, V Chen, AD Johnson
Nature Genetics 42 (7), 590 ( PDF )
Genetics and molecular biology in Candida albicans (2010)
AD Hernday, SM Noble, QM Mitrovich, AD Johnson
Methods in Enzymology 470, 737-758 ( PDF )
A phenotypic profile of the Candida albicans regulatory network (2009)
OR Homann, J Dea, SM Noble, AD Johnson
PLoS Genetics 5 (12), e1000783 ( PDF )
An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth (2009)
SL Elson, SM Noble, NV Solis, SG Filler, AD Johnson
PLoS Genetics 5 (9), e1000664 ( PDF )
Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans (2008)
OW Liu, CD Chun, ED Chow, C Chen, HD Madhani, SM Noble
Cell 135 (1), 174-188 ( PDF )
Genetics of Candida albicans, a Diploid Human Fungal Pathogen (2007)
SM Noble, AD Johnson
Annu. Rev. Genet. 41, 193-211 ( PDF )
Transcriptional Response of Candida albicans to Nitric Oxide and the Role of the YHB1 Gene in Nitrosative Stress and Virulence (2005)
BS Hromatka, SM Noble, AD Johnson
Molecular Biology of the Cell 16 (10), 4814-4826 ( PDF )
Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans (2005)
SM Noble, AD Johnson
Eukaryotic Cell 4 (2), 298-309 ( PDF )